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Science-backed probiotics.Legacy you trust.Results that deliver.

Science-backed probiotics.Legacy you trust.Results that deliver.

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VSL® Probiotics: A Legacy of Science in Every Strain.

Building on the trusted heritage of VSL#3®, VSL® Probiotics now includes innovative supplements like VSL4®, designed for everyday wellness.

Trusted worldwideA legacy built on trust and expertise.

Rooted in scienceGuided by probiotic research.

Commitment to qualityEnsuring potency and reliability.

Designed for diverse needsSupporting gut and women’s health.

A Gold Standard in Probiotics

  • A powerful probiotic medical food
  • The #1 gastroenterologist-recommended multi-strain probiotics brand†
  • Ultra-high-potency — guaranteed through expiration when stored as recommended.
  • 8 complementary probiotic strains from 3 different genera.
  • Used in clinical practice and supported by clinical and scientific research.
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VSL#3® Capsules
Best Seller
Sale
VSL#3® Capsules

For the dietary management of IBS and UC

  • 112.5 Billion CFU
  • Probiotic Medical Food
  • Refrigerated
From$131.90 $59.36
VSL#3® Powder
Sale
VSL#3® Powder

For the dietary management of IBS, UC, and pouchitis

  • 450 Billion CFU
  • Probiotic Medical Food
  • Refrigerated
From$225.90 $101.66
VSL#3® DS Powder
VSL#3® DS Powder

For the dietary management of UC and pouchitis

  • 900 Billion CFU
  • Probiotic Medical Food
  • Refrigerated
From $142.16

Probiotics Backed by Science — Designed for Everyday Wellness

  • Precision-formulated probiotic supplements that support daily health and balance.*
  • Made with probiotic strains supported by clinical and scientific evidence.
  • Shelf-stable, high-quality formulations — guaranteed through expiration when stored as recommended.
  • Developed to help with a range of needs — from digestive comfort and regularity to feminine wellness and immune support.*
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VSL4® Gut Capsules
Sale
VSL4® Gut Capsules

Supports digestive balance, regularity, and overall gut health.*

  • 30 Billion CFU
  • Probiotic Supplement
  • Shelf-stable
From$69.90 $31.46
VSL4® Vaginal Health
NEW!
VSL4® Vaginal Health

Supports vaginal microbiota balance, normal yeast and pH levels, and urinary tract health.*

  • 10 Billion CFU, Prebiotic Fiber, Essential Vitamins, Cranberry Extract
  • Probiotic Supplement
  • Shelf-stable
From $26.96

Science Over Hype.Purpose Over Promises.

Built on the legacy of VSL#3® — a probiotic trusted by healthcare professionals and recognized for its scientific rigor — VSL® Probiotics continues to advance microbiome science through targeted, high-quality formulations that support both clinical dietary management and everyday wellness.
For us, potency isn’t a number — it’s a principle. Every VSL® Probiotics formulation is developed with meaningful levels of live bacteria, manufactured under controlled conditions, and verified to maintain the labeled CFU count through expiration when stored as recommended.
Potency matters because probiotic function depends on both the quantity and vitality of live organisms that reach the gut. Even modest loss over time can affect performance, which is why every VSL® Probiotics product is designed and tested to deliver consistent strength from first dose to last.

Committed to Potency

Potent probiotic formulations guaranteed to maintain labeled CFU counts through expiration.

For probiotics to work, live microorganisms must survive both storage and digestion to reach the gut intact. Every VSL® Probiotics formulation is developed with this in mind — combining carefully selected strains, stability-enhancing formulation design, and packaging to maintain viability from manufacturing through expiration.
VSL#3® is maintained under strict cold-chain conditions — refrigerated throughout production, storage, and shipping — to help preserve live strains at their intended strength.
VSL4® products are shelf-stable and formulated with acid-resistant capsules that help protect probiotic bacteria until they reach the intestinal tract.

Designed for Viability

Carefully designed formulations that help safeguard live bacteria from production to delivery.

Our formulations are grounded in science. Each strain is selected for its documented characteristics and ability to contribute meaningfully to a balanced microbiome. This approach draws on years of probiotic research — building on well-studied formulations and evidence-backed strains to create products designed for specific microbiome needs.
Across the VSL® Probiotics family, every formulation follows the same principle: science guides each step, from strain selection to finished product. This consistent, evidence-based process ensures reliability and quality across the brand’s entire portfolio.

Science-Led Strain Selection

Thoughtfully formulated with complementary probiotic strains chosen for function and purpose.

VSL® Probiotics builds on the legacy of VSL#3® — a formulation long trusted by healthcare professionals for its quality and reliability. That foundation continues to guide how we develop every product in the VSL® Probiotics family.
Our focus is clear: to create formulations grounded in evidence, crafted with precision, and respected for their consistency — not driven by trends, but by trust earned through experience.

A Legacy of Expertise

A probiotic heritage recognized for its consistency, credibility, and professional trust.

What Our Customers Say

What OurCustomers Say

Clean Ingredients. Trusted Standards.

We believe what's not in your probiotic is just as important as what is.

Dairy-Free

Gluten-Free

No GMOs

Soy-Free

The VSL® Probiotics Difference

Medical Foods & Supplements

From medical foods formulated for the dietary management of GI conditions to supplements for daily wellness, VSL® Probiotics is made to the highest standards of quality and consistency.

Proven Potency

Up to 900 billion live bacteria per serving — verified to maintain labeled CFU counts through expiration when stored as recommended.

Evidence-Based Formulations

Formulated with probiotic strains and combinations supported by published research and guided by microbiome science.

Trusted by Professionals

Rooted in the heritage of VSL#3®—a probiotic trusted by healthcare professionals—VSL® Probiotics carries that same dedication to quality and research into every new formulation.

Medical Foods & Supplements

From medical foods formulated for the dietary management of GI conditions to supplements for daily wellness, VSL® Probiotics is made to the highest standards of quality and consistency.

Proven Potency

Up to 900 billion live bacteria per serving — verified to maintain labeled CFU counts through expiration when stored as recommended.

Evidence-Based Formulations

Formulated with probiotic strains and combinations supported by published research and guided by microbiome science.

Trusted by Professionals

Rooted in the heritage of VSL#3®—a probiotic trusted by healthcare professionals—VSL® Probiotics carries that same dedication to quality and research into every new formulation.

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